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KMID : 0356620120270040318
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Journal of Korean Society of Endocrinology
2012 Volume.27 No. 4 p.318 ~ p.322
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A Case of Latent Autoimmune Diabetes in Adults Developed after Surgical Cure of Growth Hormone Secreting Pituitary Tumor
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Kim Won-Jin
Kim Jung-Ho
Kim Young-Sook
Huh Ji-Hye
Lee Su-Jin
Park Mi-Sung
Choe Eun-Yeong
Hong Jae-Won
Lee Byung-Wan
Kang Eun-Seok
Cha Bong-Soo
Lee Eun-Jig
Lee Hyun-Chul
Park Jeong-Kyung
Lee Myung-Won
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Abstract
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Acromegaly is generally caused by a benign growth hormone (GH)-secreting pituitary adenoma. It is characterized by a wide range of complications; cardiovascular, respiratory, bone and joint, and metabolic complications. Among them, impaired glucose tolerance and diabetes mellitus, due to GH-induced insulin resistance, has been reported in approximately 16-46% and 19-56%. They are usually improved following the treatment of acromegaly, surgical or medical therapy. We report a first case of 36-year-old man who was paradoxically diagnosed with GAD antibody positive latent autoimmune diabetes in adults (LADA) after the surgical cure of acromegaly.
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KEYWORD
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Acromegaly, Type 2 diabetes mellitus
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